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Buffalo Bills: Key matchups to look forward to in each game in 2020

By Kendall Mirsky

ORCHARD PARK, NY - DECEMBER 29: Josh Allen #17 of the Buffalo Bills shakes hands with Sam Darnold #14 of the New York Jets after the game at New Era Field on December 29, 2019 in Orchard Park, New York. New York defeats Buffalo 13-6. (Photo by Brett Carlsen/Getty Images)
ORCHARD PARK, NY - DECEMBER 29: Josh Allen #17 of the Buffalo Bills shakes hands with Sam Darnold #14 of the New York Jets after the game at New Era Field on December 29, 2019 in Orchard Park, New York. New York defeats Buffalo 13-6. (Photo by Brett Carlsen/Getty Images) /
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PHILADELPHIA, PA – DECEMBER 26: Trent Williams #71 of the Washington Redskins walks off the field at the end of the first half against the Philadelphia Eagles on December 26, 2015 at Lincoln Financial Field in Philadelphia, Pennsylvania. (Photo by Mitchell Leff/Getty Images)
PHILADELPHIA, PA – DECEMBER 26: Trent Williams #71 of the Washington Redskins walks off the field at the end of the first half against the Philadelphia Eagles on December 26, 2015 at Lincoln Financial Field in Philadelphia, Pennsylvania. (Photo by Mitchell Leff/Getty Images) /

Week 13 – Bills edge rushers vs. 49ers OTs

In Week 13 the Buffalo Bills will travel to San Francisco to play the 49ers in their second primetime game of the season and first of two Monday Night Football contests. After winning the NFC last year, the 49ers don’t have a lot of holes on their roster, making this a very intriguing team matchup.

Last year showed just how effective the Kyle Shanahan running attack is and this is why this game will be won in the trenches. Win or lose, this will be a lesson filled experience for A.J. Epenesa going up against arguably the best offensive line he has seen at this point in his NFL career. Whether he lines up on the left or right side of the offense, he will have to attack either Mike McGlinchey or Trent Williams, who was acquired via trade from the Washington Redskins during the 2020 NFL Draft.

The same argument goes for Jerry Hughes, Trent Murphy, Mario Addison, or whoever McDermott/Frazier decide to line up on the edges for this game. Setting the edge against the Shanahan rushing attack is a very important factor in mitigating the efficiency of the outside zone run.

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