Final score prediction for Buffalo Bills vs. Indianapolis Colts in Week 10

Let's get to 8-2!
Miami Dolphins v Buffalo Bills
Miami Dolphins v Buffalo Bills / Bryan Bennett/GettyImages
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Over halfway through the regular season, Bills Mafia is having lots of fun seeing the Buffalo Bills be as successful as they are. Currently at 7-2, the Bills have separated themselves with the rest of the teams in the AFC East and are closer to getting towards the top of the AFC. 

They will be looking to add yet another win to their record but they must defeat the Indianapolis Colts this Sunday in order to do so. The Colts are one game below .500 at 4-5 and they are a physical team who has lost by no more than one score in their five losses. To sum it up, they don’t get blown out in games. There are times when it feels that is the only way that the Bills can win is by running up the scoreboard.

The Colts have not been friendly to the Bills in their last two regular season meeting. Aside from the fact that they have outscored Buffalo 78-20 in their last two meetings, the Bills have not win in Indianapolis since 1998, Peyton Manning’s rookie season. Another fun fact? The Colts were still in the AFC East at that time. Yeah, it’s been quite the drought.

However, the Bills now have the chance to break that drought and keep expanding their winning streak this season. It’s important for Buffalo to focus on this game, due to the fact of who they play after the Colts; the Kansas City Chiefs.

This upcoming game against the Colts could actually come back to haunt the Bills if they can’t leave with a win. It’s crucial that Buffalo takes care of business in Indianapolis before putting the major focus on Patrick Mahomes and the Chiefs.

Predicting final score for Bills vs. Colts

Indianapolis made the quarterback switch from Anthony Richardson to Joe Flacco a couple weeks ago, and that makes the offense more balanced. However, the Colts are going into Week 10 without wideout Michael Pittman or their starting center, Ryan Kelly. Flacco losing protection up front and one of the more underrated pass catchers in the game puts him in a tough spot against Buffalo.

It wouldn’t be a surprise to see the Colts try to get Jonathan Taylor going against the run defense. The good news for Buffalo is that they have shown that they can adjust when needed so as long as they don’t allow Taylor to run all over them for four quarters, Bills Mafia might be enjoying a fifth consecutive win.

Final score prediction: Bills def. Colts 28-24

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