Bills vs. Bears prediction and odds for NFL Week 16 (Chicago can’t stop Josh Allen)

Dec 11, 2022; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) rolls out of the pocket in the fourth quarter game against the New York Jets at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports
Dec 11, 2022; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) rolls out of the pocket in the fourth quarter game against the New York Jets at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports /
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The Buffalo Bills can clinch the AFC East on Christmas Eve when they head to the Windy City to take on the Chicago Bears.

They’ve won five in a row and can now use the Bears as a tune up game for the final stretch of the regular season as they try to not only lock up the division, but also clinch the No. 1 seed in the conference which comes with a first round BYE in the playoffs as well as home field advantage.

With the Bears already being eliminated from the postseason, they’ll look to play spoiler.

Can they pull off the upset, or will Buffalo clinch the division?

Let’s dive into the odds and then I’ll give you my best bet.

Bills vs. Bears Odds, Spread, and Total

Bills vs. Bears Betting Trends

  • Bills are 2-6 ATS in their last 8 games
  • The UNDER is 9-3 in the Bills’ last 12 games
  • The UNDER is 7-0 in the Bills last seven road games
  • Bills are 0-6 ATS in their last six games against NFC North opponents
  • Bears are 1-4 ATS in their last five games
  • The OVER is 7-1 in the Bears’ last eight games

Bills vs. Bears Prediction and Pick

The Bills will prove their dominance on Saturday in Chicago. They should have no issue putting up a plethora of points against the Bears defense, which has been one of the worst in the NFL this season.

The Bears are 30th in opponent yards per play, allowing 5.9 yards per snap. They’ve also allowed the second most yards per play over their last three games, allowing 6.3 yards per snap.

Their secondary has also been abysmal, allowing 8.2 yards per pass over their last three games, the third worst mark in the league over that stretch.

A big area Buffalo will be tested in is their run defense. They’ll face a Bears team that leads the NFL in run plays per game as well as yards per carry. Buffalo currently ranks 19th in opponent yards per rush, but now that they can focus in on that area, I think they’ll thrive this week.

I trust Buffalo to take care of business and win with margin on Christmas Eve.

You can track Iain’s bets on Betstamp here.

Game odds refresh periodically and are subject to change.