Buffalo Bills: Updated game-by-game predictions entering the 2021 season

Shortly after the NFL released the Buffalo Bills schedule for the 2021 season, I put together my game-by-predictions for the upcoming season. However, over the past three months, plenty has changed, for both the Bills and their opponents.

Now that the 2021 season is one week away, most of the rosters are set and unlikely to change much, so it is time to update my game-by-game predictions and what I believe will be the Buffalo Bills record this season.

Week 1: Pittsburgh Steelers at Buffalo Bills

The Buffalo Bills are opening the 2021 season at home against a franchise that has consistently been one of the best in the AFC for nearly two decades. Even this past year, the Steelers started off really great by winning their first 11 before struggling down the stretch with four losses in five games.

One of those losses was to the Bills when they won 26-15 on Sunday Night Football.

The Steelers are entering this season with a number of questions, particularly on their offensive line and with their pass rush. The offensive line lost a lot of their veterans while the defense lost Bud Dupree to free agency and Stephon Tuitt is on injured reserve and will miss this game.

This will likely be a close game as the Steelers still have Ben Rothlisberger at quarterback and Mike Tomlin on the sideline, but the Buffalo Bills pull away late in front of the home crowd to start the season with a win.

Prediction: Win (1-0)