Defensive Ends: Mario Addison, Vernon Butler
Defensive Tackles: Star Lotulelei, Harrison Phillips
When the Buffalo Bills need to get big, either in short-yardage or goal line situations, they can run out a defensive line combination like this. One of the biggest changes is that Vernon Butler, who is typically a tackle, can slide out and set the edge as defensive end.
This is a position he actually played in his final season with the Carolina Panthers when they ran a 3-4 defense. This was his best season as a pro, finishing with six sacks and eight QB hits. However, in this combination he will be expected to set the edge and get to the ball carrier.
The other change is lining up Harrison Phillips alongside Star Lotulelei and while Phillips is more of a one-tech defensive tackle, he does have some explosiveness that allows him to get into the backfield. The combination of these two would give offensive lines a challenge in moving them to create running lanes to pick up those few yards.