Bills vs. Jets prediction, odds, spread, injuries, trends for NFL Week 1

A full betting preview for NFL Week 1 edition of Monday Night Football between the Bills and Jets.

Bills quarterback Josh Allen cuts back for extra yards against the Jets.
Bills quarterback Josh Allen cuts back for extra yards against the Jets. / JAMIE GERMANO / USA TODAY NETWORK

The Buffalo Bills will face-off against the Aaron Rodgers-led New York Jets in the first edition of Monday Night Football of the 2023 season.

The AFC East is stacked this season and this is going to be an immediate measuring stick for the Jets, who hope to dethrone the Bills atop the division.

In this article, I'm going to tell you everything you need to know to bet on this game, as well as my best bet. If you want my best bet for the other 15 games as well, you can find them in this week's edition of the "Road to 272 Bets".

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Now, let's get into my betting preview for the first edition of Monday Night Football of the 2023 NFL season.

Bills vs. Jets odds, spread, and total

Bills vs. Jets betting trends

  • Bills were 8-9-1 against the spread in 2022
  • Jets were 8-9 ATS in 2022
  • The UNDER went 11-7 in Bills games in 2022
  • The UNDER went 12-5 in Jets games in 2022
  • Bills are 2-5 ATS in their last seven games against AFC East opponents
  • The UNDER is 4-1 in the last five meetings between these two teams
  • Jets are 2-16 straight up in their last 18 games against AFC East opponents
  • Jets are 1-8 ATS in their last nine games played in September

Bills vs. Jets injury reports

Buffalo Bills injury report

  • Connor McGovern - G - Questionable (leg)
  • Von Miller - LB - Out (knee)

New York Jets injury report

  • Breece Hall - RB - Questionable (knee)
  • Allen Lazard - WR - Questionable (shoulder)

Bills vs. Jets how to watch

  • Date: Monday, Sept. 11
  • Game Time: 8:15p.m. EST
  • Venue: MetLife Stadium
  • How to Watch (TV): ESPN/ABC/ESPN+
  • Buffalo Bills Record: 0-0
  • New York Jets Record: 0-0

Bills vs. Jets key players to watch

Buffalo Bills

Khalil Shakir: After the surprise release of Isaiah McKenzie, Khalil Shakir is expect to slot in as the No. 3 option in the passing game for the Bills. He showed some solid flashes last year, including hauling in three catches for 51 yards in their wild card playoff win against the Dolphins. He could be a name that's going to slot into a productive role for Buffalo in 2023.

New York Jets

Breece Hall: Sometimes I think people forget just how good Breece Hall was before he got injured last season. He ran the ball for 80 times in his rookie season, accumulating 463 yards for 5.8 yards per carry. He was the betting favorite to win Offensive Rookie of the Year at the time. Now that he's entering his second year, it's going to be interesting to see if he can move on past his injury and start right where he left off.

Bills vs. Jets prediction and pick

The Jets had one of the top defenses in the NFL last season and now they have a former MVP at QB in Aaron Rodgers, but yet I'm still not convinced enough to bet on them in Week 1. I think the Jets are a team that may get better as the season progresses, but Rodgers may need time to start to gel in a new offense with new teammates.

Also, let's not forget just how good this Bills team is. They lead the AFC last season in average scoring margin at +8.6. They seem to be somehow underrated heading into 2023, despite returning largely the same team they had last season.

The Bills are a tough task in Week 1 for a Jets team that's looking to be a contender in 2023. They may get there by the end of the season, but I don't think they'll be ready to compete at Buffalo's level quite yet.

Odds refresh periodically and are subject to change.

You can check out all of Iain's bets here!