5 key matchups for Buffalo Bills vs. Jacksonville Jaguars in Week 5

Buffalo Bills v Jacksonville Jaguars
Buffalo Bills v Jacksonville Jaguars / Douglas P. DeFelice/GettyImages
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3.) Bills’ defensive line vs. Jaguars’ RBs

Winning in the trenches on both sides of the ball will be crucial for Buffalo. While the pass rush upfront has been exceptional, they have to find a way to improve stopping the run. In three out of four games, the Bills’ defense has given up more than 100 rushing yards.

With the secondary in Buffalo being a big question after Tre White’s injury, the defensive line for the Bills may have to step up even more to shut down the Jaguars’ run game and make Trevor Lawrence win the game himself. 

Travis Etienne and company have rushed for 400 total yards on the season, which includes some carries by Lawrence himself. One of the advantages for Buffalo is that if Etienne can’t get the run game going, then Jacksonville may have to rely on the pass more than anticipated. Even beyond the defensive line, linebackers Matt Milano and Terrel Bernard could even be played more on the line of scrimmage to stuff the run.