Micah Hyde
The Buffalo Bills coaching staff won't ask Rasul Douglas to do it alone and they are likely to give him plenty of help over the top. This will be a key week for Micah Hyde as well, who does a great job playing that deep safety and ensuring there aren't big plays over the top.
Hyde has dealt with injuries a few times this season and just returned last week against the Patriots after missing two games due to a neck stinger. In that game he would have his first pass defended since Week 9 against the Bengals.
The last time he had an interception though was much longer and in fact, was back in Week 4 in the Bills' first matchup with the Dolphins. It came at a key point in the game as the Bills were holding onto a 34-20 lead and Hyde would intercept a deep throw by Tua Tagovailoa to Robbie Chosen. The Bills would end up scoring a touchdown after that turnover and the Dolphins never really got back into the game.
I would expect the Buffalo Bills to keep Micah Hyde deep to defend those big plays and he has a chance to make an impact in this role.