5 best offenses the Buffalo Bills will face in 2024
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5. San Francisco 49ers
San Francisco has the best running back in football in their backfield and possesses one of the top duos at the wide receiver position. With Christian McCaffrey, Deebo Samuel, and Brandon Aiyuk lining up for the 49ers' offense, they possess some of the best skill position players in the league. Then you add in tight end George Kittle, San Francisco is dangerous, and a top-ten offense.
What brings them down is their offensive line and quarterback. They have one of the best left tackles in the NFL, but the rest of the line is questionable. According to Pro Football Network, San Francisco's line ranks 18th in the league, second to worst among the teams on this list. Quarterback Brock Purdy is a good quarterback, but I don't believe he's better than any of them on the other teams I've listed.