Curtis Samuel
While there are questions at wide receiver, there is no doubt that whoever emerges as the top receiver is going to have real value in fantasy football. There will be managers who will go after Khalil Shakir or rookie Keon Coleman but Curtis Samuel is the wide receiver to target in fantasy football.
This is Samuel's first season with the Bills after they signed him to a three-year deal as a free agent. He previously spent time with the Panthers and Commanders and has typically been that second or third option in passing games.
However, in Buffalo he could emerge as the top receiver when considering his best season of his career was in 2020 with the Panthers. At the time, his offensive coordinator was Joe Brady and he is in a similar role with the Bills which will put him in the best position to be successful.
On top of that, Samuel saw a number of rushing attempts with Brady running the offense and that also could continue. If that does, he should be able to produce as a WR2 in fantasy football and be a great steal in the mid to late rounds of drafts.