Buffalo Bills 2022 schedule: Game-by-game predictions for every game

Josh Allen, Gabriel Davis, Buffalo Bills (Mandatory Credit: Rich Barnes-USA TODAY Sports)
Josh Allen, Gabriel Davis, Buffalo Bills (Mandatory Credit: Rich Barnes-USA TODAY Sports)
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Buffalo Bills
Micah Hyde, Buffalo Bills (Mandatory Credit: Mark Konezny-USA TODAY Sports)

Week 18: New England Patriots at Buffalo Bills

In the final regular season game of the 2022 season, the Buffalo Bills return home to face the New England Patriots. If the Bills are entering this game 14-2, there is a strong likelihood that they have the AFC East division locked up and a high playoff seed.

This could mean the team looks to rest starters and get ready for what hopefully is a deep playoff run. If that is the case, then Buffalo likely comes away with a loss here and should be happy with a regular season record of 14-3.

However, for the sake of these predictions I am going to assume they play their full roster. The sentiment from their last matchup remains in that while Buffalo can’t take Bill Belichick lightly, this roster is better than what the Patriots have and the Bills are able to come away with a win here.

Prediction: Win (15-2)

Schedule