Buffalo Bills: Ranking the difficulty of each game on 2020 schedule

EAST RUTHERFORD, NJ - SEPTEMBER 08: General view of the Special Teams line of the New York Jets in action against the Buffalo Bills at MetLife Stadium on September 8, 2019 in East Rutherford, New Jersey. (Photo by Al Pereira/Getty Images)
EAST RUTHERFORD, NJ - SEPTEMBER 08: General view of the Special Teams line of the New York Jets in action against the Buffalo Bills at MetLife Stadium on September 8, 2019 in East Rutherford, New Jersey. (Photo by Al Pereira/Getty Images) /
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MIAMI, FLORIDA – FEBRUARY 02: Jimmy Garoppolo #10 of the San Francisco 49ers throws a pass against the Kansas City Chiefs in Super Bowl LIV at Hard Rock Stadium on February 02, 2020 in Miami, Florida. The Chiefs won the game 31-20. (Photo by Focus on Sport/Getty Images)
MIAMI, FLORIDA – FEBRUARY 02: Jimmy Garoppolo #10 of the San Francisco 49ers throws a pass against the Kansas City Chiefs in Super Bowl LIV at Hard Rock Stadium on February 02, 2020 in Miami, Florida. The Chiefs won the game 31-20. (Photo by Focus on Sport/Getty Images) /

Week 13 – Away vs San Francisco 49ers

That brings us to the hardest matchup on the 2020 slate, a trip out west to take on the defending NFC Conference Champions. This primetime matchup could be the lowest scoring game of the season as the top defenses in the league square off.

While the Bills offense line improved in 2019 this 49ers defense should give them problems all game. How many times have we seen the Bills defense win a game for them, well, this feels like another game that the defense might have to get a huge play late in the fourth quarter if the Bills want to head home with a win.

Next. Predicting the winner of every Bills game in 2020. dark

Winning this game will have the Buffalo Bills feeling like a Super Bowl run is in their future for the remaining of the season.