2. Aaron Schobel
While Chris Kelsay was one of the Bills starting defensive ends for most of the 2000s, the other was Aaron Schobel. He was drafted in the second round of the 2001 NFL Draft and would go on to play nine seasons with the Buffalo Bills.
Schobel was one of the most consistent pass rushers the Buffalo Bills have had in their franchise history and is one of the reasons he is second in sacks with 78 career sacks. In his nine seasons, he had only one season with less than 6.5 sacks, which came in 2008 when he played only five games.
He would go on to have four seasons with double digit sacks and was named to the Pro Bowl in back to back years in 2006 and 2007. Aaron Schobel was one of the key pieces when the Bills had some of the better defenses in the league in early 2000s and was one of the best defensive ends to play for the Buffalo Bills.