Buffalo Bills: Matt Milano appears to suffer serious knee injury in Week 5

The Buffalo Bills entered Week 5 with a long list of injuries and missing starters like Greg Rousseau, Tre'Davious White, and Christian Benford for the game against the Jacksonville Jaguars. Unfortunately, the injuries continued into the game as two more starters left with injuries in the first quarter.

The biggest concern has to be with linebacker Matt Milano, as he left with a knee injury. The Bills have already ruled out Milano for this game which is a good indication that this is probably a serious injury.

According to Ian Rapoport, Milano did leave the sidelines on the cart with his leg in a full cast. This is another indication that this injury could be a long-term injury.

Milano has been playing incredibly football to begin the season as he already had two interceptions through the first four games. The Bills now lose a lot of experience at linebacker as the team appears to be moving forward with Dorian Williams replacing Milano and he will play alongside second-year linebacker Terrel Bernard.

Buffalo Bills list DaQuan Jones as doubtful to return with pec injury

On the same drive that Milano was hurt, the Buffalo Bills also lost defensive tackle DaQuan Jones left the game due to a pec injury. While he wasn't listed as out, it seems unlikely he will be return as the Bills have him as doubtful to return.

DaQuan Jones is another player who has been playing great football to begin the season. The Bills have done a good job against the run the past three weeks and Jones in the middle has been a big reason for that.

The Bills will look to Tim Settle and Jordan Phillips to try and fill in for the absence of DaQuan Jones for the rest of the Bills' Week 5 matchup against the Jacksonville Jaguars.