1.) Get up early and don't let up
In Weeks 2-4, the overall score that the Bills led by going into halftime was 68-24 (21-10 vs. Raiders, 16-0 vs. Commanders, 31-14 vs. Dolphins). The offense had no trouble getting up early in the first half and going into the second half, closing out the game with no issue.
That has not been the case the last two weeks as going into halftime against the Jaguars and Giants, the Bills have been down by a combined score of 17-7 (7-11 vs. Jaguars, 0-6 vs. Giants). The Bills ended up losing to Jacksonville, and barely beating the Giants late in the fourth quarter.
The Patriots have only taken the lead once going into halftime once this season (Week 3 vs. Jets). Josh Allen and the Buffalo offense will need to score early and often in order to put the pressure on the New England offense and make them go away from their planned offensive scheme going into the game.