3.) James Cook gets 20+ carries
The running game in Buffalo has been more promising at various times in games this year than the pass-attack. One of the reasons as to why is because of the versatility of James Cook and ability to gain that extra step in the open field.
In addition, backup running back Latavius Murray has been a great complimentary piece to the running game. When the Bills are able to run the ball and pick up four or five yards, the offense flows better and takes pressure off of Josh Allen.
The most carries that Cook has had in a game this season is 17, against the Las Vegas Raiders in which he eclipsed over 100 rushing yards for the first time in his career (123). It is one of the two games where Cook has 15 or more carries, and he has come with two yards of 100 rushing yards or more.
The Bills are on a short week heading into this game, and the run game should be the main focus to stay away from any turnovers, make the Buccaneers prepare for the run and hit them with a play-action pass for a big gain.