Final 2022 regular season win-loss predictions for the Buffalo Bills

Josh Allen, Buffalo Bills (Photo by Timothy T Ludwig/Getty Images)
Josh Allen, Buffalo Bills (Photo by Timothy T Ludwig/Getty Images) /
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Dan Campbell, Detroit Lions (Syndication: Detroit Free Press) /

Week 12: Buffalo Bills at Detroit Lions

What is starting to become an annual tradition, the Buffalo Bills once again will be playing a road game on Thanksgiving. In 2019, it was against the Dallas Cowboys then last year it was a primetime game against the New Orleans Saints.

In both of those games, the Bills came away with a win and they should do so again this year when they play the Detroit Lions.

However, this is a game that can’t be dismissed and this does not seem like the typical Lions team. The focal point of this year’s Hard Knocks shows a team that is going to play hard and be competitive. It may not always result in wins but they can’t be overlooked.

The Buffalo Bills always seem prepared and focused for these nationally televised games and this should be no different as they avoid a trap game and secure the win.

Prediction: Win (8-3)