1. Patrick Mahomes
The difference between number one and number two on this list is so small and there is an argument to be made that this is more 1a and 1b versus one and two. However, I believe that Patrick Mahomes is slightly more challenging and is the best quarterback the Buffalo Bills will face this season.
Mahomes has been the starting quarterback for the Kansas City Chiefs for the past three seasons. He has averaged over 4,600 passing yards and 38 passing touchdowns during that stretch. He has won a Super Bowl MVP and a regular-season MVP in that timeframe as well.
The reason that Mahomes gets a slight edge here over Brady is he is one of the most physically gifted quarterbacks in the NFL. There continues to be a debate about who has the strongest arm in the NFL between Josh Allen and Mahomes. He also brings more mobility to the position than Brady.
The Bills are set to face Patrick Mahomes and the Kansas City Chiefs in Week 5 on Sunday Night Football. There is no question that the Bills secondary will need to have their best game because they will be facing their toughest challenge of the season.